Image Challenge – Jan 1

Spot Diagnosis: What drug is this man taking that results in this characteristic skin finding?

Answer: Amiodarone can cause a slate-gray pigmentation in a photodistribution on the face. The blue colour is due to the deposition of melanin and lipofuscin contained in macrophages and endothelial cells in the dermis. The pigmentation is reversible, but may take up to a year or more to complete resolution. 

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