Question: What is the radiologic sign in the following chest x-ray? What underlying pathology does it indicate?

Answer: This x-ray demonstrates Hampton’s Hump, classically seen in pulmonary embolism.
Source: https://www.nejm.org/image-challenge%C2%A0%C2%A0%C2%A0%C2%A0?ci=20220630&startFrom=1&page=1