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Image Challenge – February 13th

Question: What type of abnormal cells are in the blood film and what disease entity can it signify?

Reference here – Maslak, P. (2010). Smudge cells – 1. ASH Image Bank. Accessed at http://imagebank.hematology.org/image/1023/smudge-cells–1 Accessed on February 13, 2022

Answer: These are smudge cells which can be seen in chronic lymphocytic leukemia or CLL. The cells in CLL can rupture when blood film slide is being prepared due to fragility of the cells given “smudge” appearance.

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